Neurotropic Infectious Agents and Cognitive Impairment in Schizophrenia
نویسندگان
چکیده
منابع مشابه
Neurotropic infectious agents and cognitive impairment in schizophrenia.
The links between infectious agents and risk for schizophrenia have been widely debated, but few investigations have focused on "epidiagnostic" effects, eg, whether exposures to infectious agents alter key clinical aspects of the disorder, such as cognitive impairment. The present theme issue evaluates epidiagnostic cognitive effects of two common infectious agents, namely Herpes Simplex Virus,...
متن کاملCognitive impairment in schizophrenia.
Cognitive functioning is moderately to severely impaired in patients with schizophrenia. This impairment is the prime driver of the significant disabilities in occupational, social, and economic functioning in patients with schizophrenia and an important treatment target. The profile of deficits in schizophrenia includes many of the most important aspects of human cognition: attention, memory, ...
متن کاملCognitive impairment in schizophrenia
Traditionally, significant cognitive impairment was thought to be evident only in elderly deteriorated patients with schizophrenia. However, over the past 25 years, evidence has accrued to challenge this view. It is becoming evident that marked cognitive impairment is, in fact, the norm and often pre-dates the illness. The recent literature has attempted to characterise the prevalence, degree a...
متن کاملPersistent infection with neurotropic herpes viruses and cognitive impairment.
BACKGROUND Herpes virus infections can cause cognitive impairment during and after acute encephalitis. Although chronic, latent/persistent infection is considered to be relatively benign, some studies have documented cognitive impairment in exposed persons that is untraceable to encephalitis. These studies were conducted among schizophrenia (SZ) patients or older community dwellers, among whom ...
متن کاملSeropositivity of neurotropic infectious agents in first-episode schizophrenia patients and the relationship with positive and negative symptoms.
BACKGROUND According to the neurodevelopmental model, schizophrenia is a disorder that occurs as a result of different etiologic factors during brain development, including viral infections. However, it is unclear whether these infections are related to the disease or whether they affect the symptom pattern. We investigated the presence of four herpes viruses (EBV, CMV, HSV-1 and HSV-2) in firs...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2012
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sbs125